(2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid

Base Information

Chemical Name:(2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid
CAS No.:1179842-79-5
Molecular Formula:C₁₉H₃₅NO₄
Molecular Weight:341.491
Hs Code.:

Synonyms:(2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid

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Chemical Property of (2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid

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Technology Process of (2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid

There total 1 articles about (2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1210404-87-7
methyl (2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetate

: 1179842-79-5
(2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid

Guidance literature:: With lithium hydroxide monohydrate; water; In tetrahydrofuran; at 50 ℃; for 3h;
DOI:10.1021/jm900372w

Reference yield:

: 1152131-10-6
(4R)-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-4-({7-methoxy-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl}oxy)-L-prolinamide

: 1179842-79-5
(2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid

: C₄₉H₆₉N₇O₉S₂

Guidance literature:: (2S)-[(tert-butoxycarbonyl)(3,3-dimethylbutyl)amino](cyclohexyl)acetic acid; With dmap; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; for 0.0833333h;

(4R)-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-4-({7-methoxy-2-[2-(propan-2-ylamino)-1,3-thiazol-4-yl]quinolin-4-yl}oxy)-L-prolinamide; In dichloromethane; at 20 ℃; for 14h;
DOI:10.1021/jm900372w