2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide

Base Information

• Chemical Name: 2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide
• CAS No.: 1016638-01-9
• Molecular Formula: C₁₅H₂₃N₃O₅S
• Molecular Weight: 357.431
• Mol file: 1016638-01-9.mol

Synonyms:2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide

Chemical Property of 2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide

There total 1 articles about 2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

ethyl [2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl]acetate (35189-65-2) → 2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide (1016638-01-9)

Guidance literature:

With hydrazine hydrate; In xylene; for 20h; Heating;

DOI:10.1016/j.bmc.2007.10.082

Reference yield: 72.0%

2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide (1016638-01-9) + 4-Chlorophenyl isothiocyanate (2131-55-7) → 1-[2-(piperidine-1-sulfonyl)-4,5-dimethoxyphenyl-acetyl]-4-(p-chlorophenyl)-thiosemicarbazide (1016638-15-5)

Guidance literature:

In ethanol; for 1h; Heating;

DOI:10.1016/j.bmc.2007.10.082

Reference yield: 66.0%

2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl-acetylhydrazide (1016638-01-9) + phenyl isothiocyanate (103-72-0) → 1-[2-(piperidine-1-sulfonyl)-4,5-dimethoxyphenyl-acetyl]-4-phenyl-thiosemicarbazide (1016638-14-4)

Guidance literature:

In ethanol; for 1h; Heating;

DOI:10.1016/j.bmc.2007.10.082

upstream raw materials:

ethyl [2-(piperidine-1-sulfonyl)-4,5-dimethoxy-phenyl]acetate

Downstream raw materials:

1-[2-(piperidine-1-sulfonyl)-4,5-dimethoxyphenyl-acetyl]-4-phenyl-thiosemicarbazide

1-[2-(piperidine-1-sulfonyl)-4,5-dimethoxyphenyl-acetyl]-4-(p-chlorophenyl)-thiosemicarbazide