Technology Process of 5,6,7,8,3',4',5'-Heptamethoxyflavone
There total 10 articles about 5,6,7,8,3',4',5'-Heptamethoxyflavone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sulfuric acid;
In
acetic acid;
for 0.05h;
Heating;
Microwave irradiation;
DOI:10.3987/COM-07-11054
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: bromine / dichloromethane / 1 h / 20 °C
2.1: copper(I) bromide / methanol; N,N-dimethyl-formamide / 1 h / 120 °C / Microwave irradiation
3.1: potassium carbonate / acetone / 0.5 h / Reflux
3.2: 4 h / 30 °C
4.1: aluminum (III) chloride / diethyl ether / 5 h / 20 °C
5.1: ethanol; water / 48 h / 20 °C / Alkaline conditions
6.1: sulfuric acid; iodine / dimethyl sulfoxide / 24 h / 80 - 85 °C
With
aluminum (III) chloride; sulfuric acid; bromine; iodine; potassium carbonate; copper(I) bromide;
In
methanol; diethyl ether; ethanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; acetone;
2.1: |Ullmann Condensation / 5.1: |Claisen-Schmidt Condensation;
DOI:10.1007/s10600-019-02605-x
