(+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate

Base Information

• Chemical Name: (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate
• CAS No.: 1334208-75-1
• Molecular Formula: C₁₅H₂₃NO₂*C₁₆H₃₂O₂
• Molecular Weight: 505.782
• Mol file: 1334208-75-1.mol

Synonyms:(+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate

Chemical Property of (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate

There total 2 articles about (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

1-hexadecylcarboxylic acid (57-10-3) + (+)-O-Demethyltramadol (144830-14-8) → (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate (1334208-75-1)

Guidance literature:

In pentane; at 20 - 30 ℃; for 24.5h; Product distribution / selectivity;

Reference yield:

(+)-O-Demethyltramadol hydrochloride (148262-77-5,185453-02-5) → (+)-(1R,2R)-3-[2-(dimethylamino)-methyl-1-hydroxycyclohexyl]phenol palmitate (1334208-75-1)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide / water / 0.65 h / 22 °C / pH 6 - 9.93

2: pentane / 24.5 h / 20 - 30 °C

With sodium hydroxide; In water; pentane;

upstream raw materials:

1-hexadecylcarboxylic acid

(+)-O-Demethyltramadol

(+)-O-Demethyltramadol hydrochloride