Technology Process of C30H27N5O5
There total 10 articles about C30H27N5O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)isoxazol-5-yl)methanol; C20H19BrN4O3;
With
caesium carbonate;
In
1,4-dioxane; ethanol; water;
at 20 ℃;
for 1h;
Inert atmosphere;
With
tetrakis(triphenylphosphine) palladium(0);
In
1,4-dioxane; ethanol; water;
for 4h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium hydroxide; water / ethanol / 2 h / Reflux
1.2: 16 h
2.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.33 h / 20 °C / Inert atmosphere
2.2: 16 h / 0 - 20 °C
3.1: caesium carbonate / ethanol; water; 1,4-dioxane / 1 h / 20 °C / Inert atmosphere
3.2: 4 h / Reflux
With
water; benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; potassium hydroxide;
In
1,4-dioxane; ethanol; water; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.33 h / 20 °C / Inert atmosphere
1.2: 16 h / 0 - 20 °C
2.1: caesium carbonate / ethanol; water; 1,4-dioxane / 1 h / 20 °C / Inert atmosphere
2.2: 4 h / Reflux
With
benzotriazol-1-ol; caesium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
1,4-dioxane; ethanol; water; N,N-dimethyl-formamide;