3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride

Base Information

• Chemical Name: 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride
• CAS No.: 128461-94-9
• Molecular Formula: C₂₀H₁₉FO₅
• Molecular Weight: 358.366
• Mol file: 128461-94-9.mol

Synonyms:3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride

Chemical Property of 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride

There total 5 articles about 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

C22H22O7 (88999-65-9,88999-66-0,130780-25-5,136459-89-7,136459-90-0) → 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride (128461-94-9)

Guidance literature:

With pyridine; hydrogen fluoride; In dichloromethane; 1.) -20 deg C, 20 min, 2.) 0 deg C, 5 min;

DOI:10.1021/ja00018a041

Reference yield: 95.0%

C20H18BrFO5 → 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride (128461-94-9)

Guidance literature:

With tri-n-butyl-tin hydride; In toluene; at 50 - 55 ℃; for 2h;

DOI:10.1016/S0022-1139(99)00026-3

Reference yield: 92.0%

acetyl 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabino-hexopyranoside (136459-89-7) → 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabinopyranosyl fluoride (128461-94-9)

Guidance literature:

With pyridine hydrogenfluoride; In dichloromethane;

DOI:10.1016/S0040-4039(01)93337-4

upstream raw materials:

acetyl 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabino-hexopyranoside

C₂₂H₂₂O₇

Methyl 3,4-di-O-benzoyl-2,6-dideoxy-α-D-arabino-hexopyranoside

C₂₀H₂₀O₆

Downstream raw materials:

Benzoic acid (R)-2-benzyloxy-1-{6-[(2R,4R,5R,6R)-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-methyl-tetrahydro-pyran-2-yl]-1,5,9,10-tetramethoxy-anthracen-2-yl}-2-methyl-pent-4-enyl ester

Benzoic acid (S)-2-benzyloxy-1-{6-[(2R,4R,5R,6R)-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-methyl-tetrahydro-pyran-2-yl]-1,5,9,10-tetramethoxy-anthracen-2-yl}-2-methyl-pent-4-enyl ester

Benzoic acid (R)-2-benzyloxy-1-{6-[(2R,4R,5R,6R)-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-methyl-tetrahydro-pyran-2-yl]-1,5-dimethoxy-9,10-dioxo-9,10-dihydro-anthracen-2-yl}-2-methyl-pent-4-enyl ester

Benzoic acid (S)-2-benzyloxy-1-{6-[(2R,4R,5R,6R)-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-methyl-tetrahydro-pyran-2-yl]-1,5-dimethoxy-9,10-dioxo-9,10-dihydro-anthracen-2-yl}-2-methyl-pent-4-enyl ester