1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene

Base Information

Chemical Name:1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene
CAS No.:1402231-83-7
Molecular Formula:C₂₃H₁₉FOS
Molecular Weight:362.468
Hs Code.:

Synonyms:1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene

Suppliers and Price of 1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene

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Technology Process of 1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene

There total 1 articles about 1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 1402231-78-0
1-methyl-4-(4-fluorophenylethynesulfonyl)benzene

: 302934-10-7
(S)-1-ethyl-2-(p-tolylsulfinyl)benzene

: 1402231-83-7
1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene

Guidance literature:: (S)-1-ethyl-2-(p-tolylsulfinyl)benzene; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 - 0 ℃; for 0.25h; Inert atmosphere;

1-methyl-4-(4-fluorophenylethynesulfonyl)benzene; In tetrahydrofuran; hexane; at -78 ℃; optical yield given as %de; Inert atmosphere;
DOI:10.1002/chem.201201607

Reference yield:

: 1402231-83-7
1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene

: (+)-(S,aS)-1-(-4-(4-fluorophenyl)buta-2,3-dien-2-yl)-2-(p-tolylsulfinyl)benzene

: (+)-(S,aR)-1-(-4-(4-fluorophenyl)buta-2,3-dien-2-yl)-2-(p-tolylsulfinyl)benzene

Guidance literature:: 1-((R)-4-(4-fluorophenyl)but-3-yn-2-yl)-2-(S)-(p-ptolylsulfinyl)benzene; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -98 - 0 ℃; Inert atmosphere;

With water; In tetrahydrofuran; hexane; at -98 - 20 ℃; for 0.25h; optical yield given as %de; Inert atmosphere;
DOI:10.1002/chem.201201607