3H-Indole,3-chloro

Base Information

• Chemical Name: 3H-Indole,3-chloro
• CAS No.: 66037-05-6
• Molecular Formula: C₈H₆ClN
• Molecular Weight: 151.595
• Mol file: 66037-05-6.mol

Synonyms:3-chloroindolenine

Chemical Property of 3H-Indole,3-chloro

Chemical Property:

Purity/Quality:

99%min ^*data from raw suppliers

3-CHLORO-3H-INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3H-Indole,3-chloro

There total 1 articles about 3H-Indole,3-chloro which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

indole (120-72-9) → 3-chloroindolenine (66037-05-6)

Guidance literature:

With tert-butylhypochlorite; triethylamine; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/j.tetlet.2011.01.051

Reference yield:

3-chloroindolenine (66037-05-6) → 3-chloro-1H-indole (16863-96-0)

Guidance literature:

With 2,2,2-trifluoroacetamide; sodium hydride; In tetrahydrofuran; at 0 - 20 ℃;

3-chloroindolenine; With 15-crown-5; In tetrahydrofuran; at -78 - 0 ℃;

DOI:10.1016/j.tetlet.2011.01.051

upstream raw materials:

indole

Downstream raw materials:

3-chloro-1H-indole

Refernces