1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

Base Information

Chemical Name:1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride
CAS No.:60284-77-7
Molecular Formula:C₃₁H₃₄F₃NO₄*ClH
Molecular Weight:578.071
Hs Code.:

Synonyms:1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

Suppliers and Price of 1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

There total 4 articles about 1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 58113-30-7
4-(3-chloropropoxy)-3-methoxyacetophenone

: 58113-26-1
α-phenyl-α-<3-(trifluoromethyl)phenyl>-4-piperidinemethanol

: 60284-77-7
1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

Guidance literature:: With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide; Heating;
DOI:10.1021/jm00121a022

Reference yield:

: 401-78-5
3-bromo-1-trifluoromethylbenzene

: 60284-77-7
1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

2: 25 percent / Na₂CO₃, KI / dimethylformamide / Heating

With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide;
DOI:10.1021/jm00121a022

Reference yield:

: 25519-79-3
1-(4-benzoylpiperidin-1-yl)ethanone

: 60284-77-7
1-[4-(3-{4-[Hydroxy-phenyl-(3-trifluoromethyl-phenyl)-methyl]-piperidin-1-yl}-propoxy)-3-methoxy-phenyl]-ethanone; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

2: 25 percent / Na₂CO₃, KI / dimethylformamide / Heating

With sodium carbonate; potassium iodide; In N,N-dimethyl-formamide;
DOI:10.1021/jm00121a022