N₂-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-4-(1-phenylethyl)-1,2(R)-piperazinedicarboxamide

Base Information

• Chemical Name: N₂-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-4-(1-phenylethyl)-1,2(R)-piperazinedicarboxamide
• CAS No.: 281195-39-9
• Molecular Formula: C₃₃H₄₁N₇O₂
• Molecular Weight: 567.734

Synonyms:N₂-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-4-(1-phenylethyl)-1,2(R)-piperazinedicarboxamide

Chemical Property of N₂-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-4-(1-phenylethyl)-1,2(R)-piperazinedicarboxamide

Chemical Property:

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Technology Process of N₂-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-4-(1-phenylethyl)-1,2(R)-piperazinedicarboxamide

There total 1 articles about N₂-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-4-(1-phenylethyl)-1,2(R)-piperazinedicarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

N2-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-1,2(R)-piperazinedicarboxamide (281197-50-0) + (1-chloroethyl)benzene (672-65-1) → N2-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N1-cyclohexyl-4-(1-phenylethyl)-1,2(R)-piperazinedicarboxamide (281195-39-9)

Guidance literature:

With triethylamine; In 1,4-dioxane; at 105 ℃; for 12h;

upstream raw materials:

N₂-[2-[1-[(4-cyanophenyl)methyl]-1H-imidazol-5-yl]ethyl]-N₁-cyclohexyl-1,2(R)-piperazinedicarboxamide

(1-chloroethyl)benzene

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