2,2-Di{4-[(di-tert-butoxyphosphoryl)(difluoro)methyl]benzyl}-3-methoxy-3-oxopropanoic acid

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Chemical Name:2,2-Di{4-[(di-tert-butoxyphosphoryl)(difluoro)methyl]benzyl}-3-methoxy-3-oxopropanoic acid
CAS No.:261176-03-8
Molecular Formula:C₃₆H₅₂F₄O₁₀P₂
Molecular Weight:782.744
Hs Code.:

Synonyms:2,2-Di{4-[(di-tert-butoxyphosphoryl)(difluoro)methyl]benzyl}-3-methoxy-3-oxopropanoic acid

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Chemical Property of 2,2-Di{4-[(di-tert-butoxyphosphoryl)(difluoro)methyl]benzyl}-3-methoxy-3-oxopropanoic acid

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Technology Process of 2,2-Di{4-[(di-tert-butoxyphosphoryl)(difluoro)methyl]benzyl}-3-methoxy-3-oxopropanoic acid

There total 3 articles about 2,2-Di{4-[(di-tert-butoxyphosphoryl)(difluoro)methyl]benzyl}-3-methoxy-3-oxopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 261176-00-5
(4-bromomethylphenyl) difluoromethylphosphonic acid di-tert-butyl ester

: 261176-03-8
2,2-Di{4-[(di-tert-butoxyphosphoryl)(difluoro)methyl]benzyl}-3-methoxy-3-oxopropanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NaH / dimethylformamide

2: NaH / dimethylformamide

With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmcl.2003.11.048