3-[2-(2-chlorophenyl)vinyl]-2-quinoxalinyl phenyl sulfide

Base Information

• Chemical Name: 3-[2-(2-chlorophenyl)vinyl]-2-quinoxalinyl phenyl sulfide
• CAS No.: 366018-64-6
• Molecular Formula: C₂₂H₁₅ClN₂S
• Molecular Weight: 374.893
• Mol file: 366018-64-6.mol

Synonyms:2-[(E)-2-(2-Chloro-phenyl)-vinyl]-3-phenylsulfanyl-quinoxaline

Chemical Property of 3-[2-(2-chlorophenyl)vinyl]-2-quinoxalinyl phenyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[2-(2-chlorophenyl)vinyl]-2-quinoxalinyl phenyl sulfide

There total 4 articles about 3-[2-(2-chlorophenyl)vinyl]-2-quinoxalinyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

thiophenol (108-98-5) + 2-Chloro-3-[(E)-2-(2-chloro-phenyl)-vinyl]-quinoxaline (53047-14-6) → 2-[(E)-2-(2-Chloro-phenyl)-vinyl]-3-phenylsulfanyl-quinoxaline (366018-64-6)

Guidance literature:

With triethylamine; In methanol; Heating;

Reference yield:

3-methyl-2-oxo-1,2-dihydroquinoxaline (14003-34-0) → 2-[(E)-2-(2-Chloro-phenyl)-vinyl]-3-phenylsulfanyl-quinoxaline (366018-64-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 98 percent / 3 h / 180 °C

2: 97 percent / DMF; POCl₃ / 0.75 h / 105 °C

3: 96 percent / Et₃N / methanol / Heating

With triethylamine; N,N-dimethyl-formamide; trichlorophosphate; In methanol;

Reference yield:

1,2-diamino-benzene (95-54-5) → 2-[(E)-2-(2-Chloro-phenyl)-vinyl]-3-phenylsulfanyl-quinoxaline (366018-64-6)

Guidance literature:

Multi-step reaction with 4 steps

1: 75 percent / HCl / H₂O / 0.25 h / 20 °C

2: 98 percent / 3 h / 180 °C

3: 97 percent / DMF; POCl₃ / 0.75 h / 105 °C

4: 96 percent / Et₃N / methanol / Heating

With hydrogenchloride; triethylamine; N,N-dimethyl-formamide; trichlorophosphate; In methanol; water;

upstream raw materials:

thiophenol

2-Chloro-3-[(E)-2-(2-chloro-phenyl)-vinyl]-quinoxaline

3-methyl-2-oxo-1,2-dihydroquinoxaline

1,2-diamino-benzene

Downstream raw materials:

2-Benzenesulfonyl-3-[(E)-2-(2-chloro-phenyl)-vinyl]-quinoxaline