cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide

Base Information

• Chemical Name: cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide
• CAS No.: 1174132-94-5
• Molecular Formula: C₁₅H₂₂N₂O₂
• Molecular Weight: 262.352
• Mol file: 1174132-94-5.mol

Synonyms:cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide

Chemical Property of cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide

Chemical Property:

Purity/Quality:

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Technology Process of cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide

There total 1 articles about cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(2-aminomethyl-4-methyl-pyridin-3-yl)-methanol (1064678-16-5) + cyclohexanylcarbonyl chloride (2719-27-9) → cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide (1174132-94-5)

Guidance literature:

With sodium carbonate; In dichloromethane; water; at 0 ℃; for 2.5h;

DOI:10.1021/jm9002445

Reference yield:

cyclohexanecarboxylic acid (3-hydroxymethyl-4-methylpyridin-2-ylmethyl)-amide (1174132-94-5) → C15H21ClN2O (1174132-48-9)

Guidance literature:

With thionyl chloride; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/jm9002445

upstream raw materials:

(2-aminomethyl-4-methyl-pyridin-3-yl)-methanol

cyclohexanylcarbonyl chloride

Downstream raw materials:

C₁₅H₂₁ClN₂O