6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide

Base Information

• Chemical Name: 6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide
• CAS No.: 103143-21-1
• Molecular Formula: Br*C₂₀H₂₂NO₄
• Molecular Weight: 420.303
• Mol file: 103143-21-1.mol

Synonyms:6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide

Chemical Property of 6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide

There total 1 articles about 6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6,7-dimethoxy-3,4-dihydro-isoquinoline (3382-18-1) + 2-Bromo-4'-methoxyacetophenone (2632-13-5) → 6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide (103143-21-1)

Guidance literature:

In N,N-dimethyl-formamide; for 0.333333h; Heating;

DOI:10.1055/s-1985-31434

Reference yield: 87.0%

6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide (103143-21-1) → 2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-methoxy-phenyl)-ethanone (67902-65-2)

Guidance literature:

With tri-n-butyl-tin hydride; In methanol; for 0.0833333h; Ambient temperature;

DOI:10.1055/s-1985-31434

Reference yield: 70.0%

nitrostyrene (5153-67-3) + 6,7-dimethoxy-2-(4-methoxyphenacyl)-3,4-dihydroisoquinolinium bromide (103143-21-1) → C28H28O6N2

Guidance literature:

With triethylamine; In ethanol; at 20 ℃;

DOI:10.1055/s-2007-977461

upstream raw materials:

6,7-dimethoxy-3,4-dihydro-isoquinoline

2-Bromo-4'-methoxyacetophenone

Downstream raw materials:

2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-1-(4-methoxy-phenyl)-ethanone