(R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

Base Information

Chemical Name:(R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol
CAS No.:1620567-18-1
Molecular Formula:C₂₂H₁₈BrN₃O₂
Molecular Weight:436.308
Hs Code.:

Synonyms:(R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

Suppliers and Price of (R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

There total 5 articles about (R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.28%

: 1620567-60-3
C₂₂H₁₈BrN₃O₂

: 1620567-18-1
(R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

Guidance literature:: C₂₂H₁₈BrN₃O₂; In methanol; at 20 ℃; for 0.25h;

With aluminum (III) chloride; In methanol; at 75 - 77 ℃;
DOI:10.1016/j.ejmech.2014.06.019

Reference yield:

: 1620567-31-8
C₁₅H₁₂N₂O

: 1620567-18-1
(R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: ethanol / 0.33 h / 20 °C

1.2: 0.25 h

1.3: 70 - 72 °C

2.1: sodium hypochlorite / dichloromethane / 0.5 h / 20 °C

2.2: 50 - 52 °C

3.1: methanol / 0.25 h / 20 °C

3.2: 75 - 77 °C

With sodium hypochlorite; In methanol; ethanol; dichloromethane;
DOI:10.1016/j.ejmech.2014.06.019

Reference yield:

: 1620567-42-1
C₂₂H₁₈BrN₃O

: 1620567-18-1
(R)-2-(4'-bromophenyl)-3-(4'-hydroxyphenyl)-1,2,3,5-tetrahydrobenzo[4,5]imidazo[1,2-c]pyrimidin-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hypochlorite / dichloromethane / 0.5 h / 20 °C

1.2: 50 - 52 °C

2.1: methanol / 0.25 h / 20 °C

2.2: 75 - 77 °C

With sodium hypochlorite; In methanol; dichloromethane;
DOI:10.1016/j.ejmech.2014.06.019