1,2-diphenyl-3-tosylhexahydropyrimidine

Base Information

• Chemical Name: 1,2-diphenyl-3-tosylhexahydropyrimidine
• CAS No.: 1322719-64-1
• Molecular Formula: C₂₃H₂₄N₂O₂S
• Molecular Weight: 392.522
• Mol file: 1322719-64-1.mol

Synonyms:1,2-diphenyl-3-tosylhexahydropyrimidine

Chemical Property of 1,2-diphenyl-3-tosylhexahydropyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-diphenyl-3-tosylhexahydropyrimidine

There total 4 articles about 1,2-diphenyl-3-tosylhexahydropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

N-(3-(benzyl(phenyl)amino)propyl)-4-methylbenzenesulfonamide (1322719-63-0) → 1,2-diphenyl-3-tosylhexahydropyrimidine (1322719-64-1)

Guidance literature:

With Ru(bpy)3Cl₂; potassium tert-butylate; oxygen; In methanol; at 20 ℃; for 33h; Irradiation;

DOI:10.1039/c1cc12203g

Reference yield:

C21H26N2O3 (1322719-62-9) → 1,2-diphenyl-3-tosylhexahydropyrimidine (1322719-64-1)

Guidance literature:

Multi-step reaction with 4 steps

1: trifluoroacetic acid / dichloromethane / 20 °C

2: tetrahydrofuran / 0 °C / Reflux

3: pyridine / dichloromethane / 0 - 20 °C

4: Ru(bpy)3Cl₂; potassium tert-butylate; oxygen / methanol / 33 h / 20 °C / Irradiation

With pyridine; Ru(bpy)3Cl₂; potassium tert-butylate; oxygen; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1039/c1cc12203g

Reference yield:

N1-benzyl-N1-phenylpropane-1,3-diamine (93537-51-0) → 1,2-diphenyl-3-tosylhexahydropyrimidine (1322719-64-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 0 - 20 °C

2: Ru(bpy)3Cl₂; potassium tert-butylate; oxygen / methanol / 33 h / 20 °C / Irradiation

With pyridine; Ru(bpy)3Cl₂; potassium tert-butylate; oxygen; In methanol; dichloromethane;

DOI:10.1039/c1cc12203g

upstream raw materials:

N-(3-(benzyl(phenyl)amino)propyl)-4-methylbenzenesulfonamide

N¹-benzyl-N¹-phenylpropane-1,3-diamine

C₁₆H₁₈N₂O

C₂₁H₂₆N₂O₃