6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

Base Information

Chemical Name:6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine
CAS No.:245092-62-0
Molecular Formula:C₂₂H₃₅NO₃SSi
Molecular Weight:421.676
Hs Code.:

Synonyms:6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

Suppliers and Price of 6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

There total 5 articles about 6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 245092-61-9
(1S,4S)-N-but-3-enyl-N-[4-(tert-butyldimethylsilanyloxy)cyclopent-2-enyl]-4-methylbenzene sulfonamide

: 245092-62-0
6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

Guidance literature:: With ethene; Grubbs catalyst first generation; In dichloromethane; at 25 ℃; for 5h;
DOI:10.1016/S0040-4020(99)00299-9

Reference yield:

: 60410-16-4
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate

: 245092-62-0
6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / imidazole / dimethylformamide / 25 °C

2: 100 percent / NEt₃; CH₃OH / 18 h / 25 °C

3: 87 percent / tributylphosphine; azodicarboxylic dipiperidide / benzene

4: 96 percent / C₂H₄ / Cl₂(PCy₃)2Ru=CHPh / CH₂Cl₂ / 5 h / 25 °C

With 1H-imidazole; methanol; ethene; tributylphosphine; triethylamine; 1,1'-azodicarbonyl-dipiperidine; Grubbs catalyst first generation; In dichloromethane; N,N-dimethyl-formamide; benzene; 1: Substitution / 2: Hydrolysis / 3: Mitsunobu reaction / 4: Rearrangement;
DOI:10.1016/S0040-4020(99)00299-9

Reference yield:

: 120520-91-4
(1R,4S)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enol

: 245092-62-0
6-[2-(tert-butyldimethylsilanyloxy)but-3-enyl]-1-(toluene-4-sulfonyl)-1,2,5,6-tetrahydropyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / tributylphosphine; azodicarboxylic dipiperidide / benzene

2: 96 percent / C₂H₄ / Cl₂(PCy₃)2Ru=CHPh / CH₂Cl₂ / 5 h / 25 °C

With ethene; tributylphosphine; 1,1'-azodicarbonyl-dipiperidine; Grubbs catalyst first generation; In dichloromethane; benzene; 1: Mitsunobu reaction / 2: Rearrangement;
DOI:10.1016/S0040-4020(99)00299-9