(2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone

Base Information

Chemical Name:(2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone
CAS No.:1088994-00-6
Molecular Formula:C₁₆H₂₀N₄O₂
Molecular Weight:300.36
Hs Code.:

Synonyms:(2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone

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Chemical Property of (2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone

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Technology Process of (2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone

There total 12 articles about (2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1001401-62-2
2-(2H-1,2,3-triazol-2-yl)benzoic acid

: ((3R,6R)-6-methylpiperidin-3-yl)methanol hydrochloride

: 1088994-00-6
(2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone

Guidance literature:: 2-(2H-1,2,3-triazol-2-yl)benzoic acid; With thionyl chloride; for 1h; Reflux;

((3R,6R)-6-methylpiperidin-3-yl)methanol hydrochloride; With sodium hydroxide; In water; toluene; at 10 ℃; for 12h;

Reference yield:

: C₂₅H₂₅N₇O₃

: 1088994-00-6
(2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone

Guidance literature:: With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃;

Reference yield:

: 1001401-62-2
2-(2H-1,2,3-triazol-2-yl)benzoic acid

: (7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl)methanesulfonic acid [(3R,6R)-6-methylpiperidin-3-yl]methanol

: 1088994-00-6
(2-(2H-1.2.3-triazol-2-yl)phenyl )((2R,5R)-5-(hydroxymethyl)-2-methylpiperidin-1-yl)methanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 20 ℃; for 16h;