(S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane

Base Information

• Chemical Name: (S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane
• CAS No.: 210486-87-6
• Molecular Formula: C₁₂H₁₅FO₂S
• Molecular Weight: 242.314
• Mol file: 210486-87-6.mol

Synonyms:(S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane

Chemical Property of (S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

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Technology Process of (S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane

There total 1 articles about (S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(2S,3R)-1-Bromo-2-fluoromethyl-3-((R)-toluene-4-sulfinyl)-butan-2-ol (210486-94-5) → (S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane (210486-87-6)

Guidance literature:

With triethylamine; for 5h; Ambient temperature;

DOI:10.1016/S0040-4020(98)83042-1

Reference yield: 95.0%

benzylamine (100-46-9) + (S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane (210486-87-6) → (2S,3R)-1-Benzylamino-2-fluoromethyl-3-((R)-toluene-4-sulfinyl)-butan-2-ol

Guidance literature:

In tetrahydrofuran; for 48h; Ambient temperature;

DOI:10.1016/S0040-4020(98)83042-1

Reference yield: 65.0%

(S)-2-Fluoromethyl-2-[(R)-1-((R)-toluene-4-sulfinyl)-ethyl]-oxirane (210486-87-6) → (2S,3R)-2-Fluoromethyl-3-((R)-toluene-4-sulfinyl)-butane-1,2-diol

Guidance literature:

With perchloric acid; In tetrahydrofuran; water; for 120h; Ambient temperature;

DOI:10.1016/S0040-4020(98)83042-1

upstream raw materials:

(2S,3R)-1-Bromo-2-fluoromethyl-3-((R)-toluene-4-sulfinyl)-butan-2-ol

Downstream raw materials:

(2S,3R)-1-Fluoro-2-methyl-3-((R)-toluene-4-sulfinyl)-butan-2-ol