4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

Base Information

Chemical Name:4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide
CAS No.:1215011-15-6
Molecular Formula:C₂₇H₃₀N₆O₂S
Molecular Weight:502.64
Hs Code.:

Synonyms:4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

Suppliers and Price of 4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

There total 5 articles about 4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 5271-26-1
m-phenylpiperazine

: 1215013-67-4
4-(2-chloro-pyridin-4-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

: 1215011-15-6
4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

Guidance literature:: With sodium hydrogencarbonate; In ethanol; at 155 ℃; for 2h; Microwave irradiation; Sealed tube;
DOI:10.1021/jm500809c

Reference yield: 55.0%

: 1215011-15-6
4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

Guidance literature:: In ethanol; at 155 ℃; for 2h;

Reference yield:

: 98-58-8
4-bromobenzenesulfonyl chloride

: 1215011-15-6
4-[2-(3-phenyl-piperazin-1-yl)-pyridin-4-yl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 24 h / 20 °C / Inert atmosphere

2: potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / N,N-dimethyl-formamide; water / 1 h / 130 °C / Inert atmosphere; Microwave irradiation

3: sodium hydrogencarbonate / ethanol / 2 h / 155 °C / Microwave irradiation; Sealed tube

With pyridine; potassium phosphate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; sodium hydrogencarbonate; In ethanol; water; N,N-dimethyl-formamide; 2: |Suzuki Coupling;
DOI:10.1021/jm500809c