C₄₃H₅₈O₅

Base Information

• Chemical Name: C₄₃H₅₈O₅
• CAS No.: 1246949-32-5
• Molecular Formula: C₄₃H₅₈O₅
• Molecular Weight: 654.931
• Mol file: 1246949-32-5.mol

Synonyms:C₄₃H₅₈O₅

Chemical Property of C₄₃H₅₈O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₃H₅₈O₅

There total 16 articles about C₄₃H₅₈O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

C41H56O4 (1246949-31-4) + acetic anhydride (108-24-7) → C43H58O5 (1246949-32-5)

Guidance literature:

With pyridine hydrochloride; at 135 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol1019663

Reference yield:

3-OTBS-11-ketotigogenin (1246949-44-9) → C43H58O5 (1246949-32-5)

Guidance literature:

Multi-step reaction with 5 steps

1.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

3.1: lithium aluminium tetrahydride / tetrahydrofuran / -10 °C / Inert atmosphere; Reflux

4.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere

4.2: 0 °C / Inert atmosphere; Reflux

5.1: pyridine hydrochloride / 2 h / 135 °C / Inert atmosphere

With lithium aluminium tetrahydride; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; pyridine hydrochloride; sodium hydride; triphenylphosphine; In tetrahydrofuran; mineral oil; 2.1: Mitsunobu reaction / 5.1: Marker's degradation;

DOI:10.1021/jo102054r

Reference yield:

C34H46O5 (1246949-45-0) → C43H58O5 (1246949-32-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / -10 °C / Inert atmosphere; Reflux

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 - 20 °C / Inert atmosphere

2.2: 0 °C / Inert atmosphere; Reflux

3.1: pyridine hydrochloride / 2 h / 135 °C / Inert atmosphere

With lithium aluminium tetrahydride; pyridine hydrochloride; sodium hydride; In tetrahydrofuran; mineral oil; 3.1: Marker's degradation;

DOI:10.1021/jo102054r

upstream raw materials:

C₄₁H₅₆O₄

acetic anhydride

3-OTBS-11-ketotigogenin

C₃₄H₄₆O₅

Downstream raw materials:

C₃₇H₅₀O₄

C₄₃H₅₈O₇