16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate

Base Information

• Chemical Name: 16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate
• CAS No.: 385372-32-7
• Molecular Formula: C₃₁H₄₄O₇S
• Molecular Weight: 560.752
• Mol file: 385372-32-7.mol

Synonyms:16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate

Chemical Property of 16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate

There total 2 articles about 16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

p-toluenesulfonyl chloride (98-59-9) + 3β,17α-diacetoxy-16β-hydroxymethyl-5α-androstane (385372-08-7) → 16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate (385372-32-7)

Guidance literature:

In pyridine; at 20 ℃; for 24h;

DOI:10.1016/S0039-128X(01)00113-1

Reference yield:

16β-acetoxymethyl-5α-androstane-3β,17α-diacetate (359888-06-5) → 16β-toluene-p-sulfonyloxymethyl-5α-androstane-3β,17α-diacetate (385372-32-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / 0.1 h / with 90 W microwave

2: 89 percent / pyridine / 24 h / 20 °C

In pyridine;

DOI:10.1016/S0039-128X(01)00113-1

upstream raw materials:

p-toluenesulfonyl chloride

3β,17α-diacetoxy-16β-hydroxymethyl-5α-androstane

16β-acetoxymethyl-5α-androstane-3β,17α-diacetate