(2S,3R)-methyl N-((S)-tert-butylsulfinyl)-3-hydroxy-3-(3-methoxyphenyl)-2-phenyl-propanimidate

Base Information

• Chemical Name: (2S,3R)-methyl N-((S)-tert-butylsulfinyl)-3-hydroxy-3-(3-methoxyphenyl)-2-phenyl-propanimidate
• CAS No.: 1582229-99-9
• Molecular Formula: C₂₁H₂₇NO₄S
• Molecular Weight: 389.516
• Mol file: 1582229-99-9.mol

Synonyms:(2S,3R)-methyl N-((S)-tert-butylsulfinyl)-3-hydroxy-3-(3-methoxyphenyl)-2-phenyl-propanimidate

Chemical Property of (2S,3R)-methyl N-((S)-tert-butylsulfinyl)-3-hydroxy-3-(3-methoxyphenyl)-2-phenyl-propanimidate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (2S,3R)-methyl N-((S)-tert-butylsulfinyl)-3-hydroxy-3-(3-methoxyphenyl)-2-phenyl-propanimidate

There total 1 articles about (2S,3R)-methyl N-((S)-tert-butylsulfinyl)-3-hydroxy-3-(3-methoxyphenyl)-2-phenyl-propanimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(Ss)-N-tert-butylsulfinyl-2-phenylethanimidate (1582229-81-9) + 3-methoxy-benzaldehyde (591-31-1) → (2S,3R)-methyl N-((S)-tert-butylsulfinyl)-3-hydroxy-3-(3-methoxyphenyl)-2-phenyl-propanimidate (1582229-99-9)

Guidance literature:

With titanium(IV) dichlorodiisopropylate; triethylamine; In dichloromethane; at 20 ℃; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/ol500520h

upstream raw materials:

(Ss)-N-tert-butylsulfinyl-2-phenylethanimidate

3-methoxy-benzaldehyde