tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate

Base Information

• Chemical Name: tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate
• CAS No.: 1204324-84-4
• Molecular Formula: C₂₇H₄₃NO₅Si
• Molecular Weight: 489.728
• Mol file: 1204324-84-4.mol

Synonyms:tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate

Chemical Property of tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate

There total 1 articles about tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

(Z)-1-(tert-butyldimethylsilyl)-3-(3-methoxyphenyl)prop-2-en-1-ol (1204324-75-3) + 2-tert-butoxycarbonylamino-hex-5-enoic acid (214206-61-8) → tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate (1204324-84-4)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/j.tet.2009.10.051

Reference yield:

tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate (1204324-84-4) → C27H43NO5Si + C27H43NO5Si

Guidance literature:

tert-butyl 1-(((Z)-3-(3-methoxyphenyl)-1-(tert-butyldimethylsi-lyl)allyloxy)-carbonyl)pent-4-enylcarbamate; With n-butyllithium; diisopropylamine; zinc(II) chloride; In tetrahydrofuran; diethyl ether; hexane; at -78 - 20 ℃; for 2h;

With hydrogenchloride; In tetrahydrofuran; diethyl ether; hexane; water; pH=1; stereoselective reaction; Inert atmosphere;

DOI:10.1016/j.tet.2009.10.051

upstream raw materials:

(Z)-1-(tert-butyldimethylsilyl)-3-(3-methoxyphenyl)prop-2-en-1-ol

2-tert-butoxycarbonylamino-hex-5-enoic acid