4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane

Base Information

• Chemical Name: 4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane
• CAS No.: 73882-20-9
• Molecular Formula: C₁₆H₁₈O
• Molecular Weight: 226.318
• Mol file: 73882-20-9.mol

Synonyms:4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane

Chemical Property of 4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane

There total 1 articles about 4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

2,5-dehydro-4-protoadamantanone (63609-75-6) + phenyllithium (591-51-5) → 4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane (73882-20-9)

Guidance literature:

In diethyl ether; benzene; 1.) 0 deg C, 1 h, 2.) room temperature, 1 h;

DOI:10.1021/ja00526a016

Reference yield:

4-endo-hydroxy-4-exo-phenyl-2,5-dehydroprotoadamantane (73882-20-9) → 4-phenyl-2,5-dehydro-4-protoadamantyl cation (73882-18-5)

Guidance literature:

With fluorosulfonylchloride; fluorosulphonic acid; at -78 ℃; Yield given;

DOI:10.1021/ja00526a016

upstream raw materials:

2,5-dehydro-4-protoadamantanone

phenyllithium

Downstream raw materials:

4-phenyl-2,5-dehydro-4-protoadamantyl cation