tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester

Base Information

• Chemical Name: tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester
• CAS No.: 151012-18-9
• Molecular Formula: C₄₉H₅₉ClN₆O₁₁
• Molecular Weight: 943.494

Synonyms:tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester

Chemical Property of tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester

There total 3 articles about tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Nε-(2-chlorobenzyloxycarbonyl)-Nα-methyllysine methyl ester → tris(benzyloxycarbonyl)-L-arginyl-Nα-methyl-Nε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester (151012-18-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 54 percent / CH₂Cl₂ / 4 h

2: 92 percent / 1N NaOH / methanol / 0 - 20 °C

3: 1.) H₂SO₄ / 1.) dioxane, 10 min, 2.) dioxane, 6 h

4: N-methylmorpholine / CH₂Cl₂ / 5 h / Ambient temperature

With 4-methyl-morpholine; sodium hydroxide; sulfuric acid; In methanol; dichloromethane;

DOI:10.1021/jm9508043

Reference yield:

Boc-[N-MeLys(ClZ)]-OH (151012-17-8) → tris(benzyloxycarbonyl)-L-arginyl-Nα-methyl-Nε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester (151012-18-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) H₂SO₄ / 1.) dioxane, 10 min, 2.) dioxane, 6 h

2: N-methylmorpholine / CH₂Cl₂ / 5 h / Ambient temperature

With 4-methyl-morpholine; sulfuric acid; In dichloromethane;

DOI:10.1021/jm9508043

Reference yield:

Nα-(tert-butoxycarbonyl)-Nα-methyl-Nε-(2-chlorobenzyloxycarbonyl)-L-lysine methyl ester (151012-16-7) → tris(benzyloxycarbonyl)-L-arginyl-Nα-methyl-Nε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester (151012-18-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / 1N NaOH / methanol / 0 - 20 °C

2: 1.) H₂SO₄ / 1.) dioxane, 10 min, 2.) dioxane, 6 h

3: N-methylmorpholine / CH₂Cl₂ / 5 h / Ambient temperature

With 4-methyl-morpholine; sodium hydroxide; sulfuric acid; In methanol; dichloromethane;

DOI:10.1021/jm9508043

upstream raw materials:

Boc-[N-MeLys(ClZ)]-OH

N^α-(tert-butoxycarbonyl)-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine methyl ester

Downstream raw materials:

tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 151012-18-9 tris(benzyloxycarbonyl)-L-arginyl-N^α-methyl-N^ε-(2-chlorobenzyloxycarbonyl)-L-lysine tert-butyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send