(S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

Base Information

Chemical Name:(S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate
CAS No.:1373348-82-3
Molecular Formula:C₂₂H₂₁ClFN₃O₅
Molecular Weight:461.877
Hs Code.:

Synonyms:(S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

Suppliers and Price of (S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

There total 3 articles about (S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1373348-79-8
(S)-3-chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl chloroformate

: 93246-53-8
3-fluoro-4-(morpholinyl)aniline

: 1373348-82-3
(S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

Guidance literature:: With potassium carbonate; In dichloromethane; at 20 ℃;
DOI:10.3998/ark.5550190.0013.605

Reference yield:

: 136918-14-4,85-41-6
phthalimide

: 1373348-82-3
(S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / isopropyl alcohol / 5 h / Reflux

2: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

3: potassium carbonate / dichloromethane / 20 °C

With potassium carbonate; triethylamine; In tetrahydrofuran; dichloromethane; isopropyl alcohol;
DOI:10.3998/ark.5550190.0013.605

Reference yield:

: 148857-42-5
2-((S)-3-chloro-2-hydroxypropyl)isoindoline-1,3-dione

: 1373348-82-3
(S)-3-Chloro-1-(1,3-dioxoisoindolin-2-yl)propan-2-yl-3-fluoro-4-morpholinophenylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 20 °C / Inert atmosphere

2: potassium carbonate / dichloromethane / 20 °C

With potassium carbonate; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.3998/ark.5550190.0013.605