2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

Base Information

Chemical Name:2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate
CAS No.:1350743-80-4
Molecular Formula:C₂₂H₂₁N₅O₄
Molecular Weight:419.44
Hs Code.:

Synonyms:2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

Suppliers and Price of 2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

There total 4 articles about 2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)amino]acetic acid

: 2-acetoxybenzoic acid hydrazide

: 1350743-80-4
2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

Guidance literature:: With trichlorophosphate; Reflux;
DOI:10.1016/j.bmcl.2011.10.057

Reference yield:

: 529-68-0
ethyl acetylsalicylate

: 1350743-80-4
2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 24 h / Reflux

2: trichlorophosphate / Reflux

With hydrazine hydrate; trichlorophosphate; In ethanol;
DOI:10.1016/j.bmcl.2011.10.057

Reference yield:

: 83-07-8
4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one

: 1350743-80-4
2-(5-{[2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-ylamino]methyl}-1,3,4-oxadiazol-2-yl)phenyl acetate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 8 h / Reflux

2: trichlorophosphate / Reflux

With potassium carbonate; trichlorophosphate; In acetone;
DOI:10.1016/j.bmcl.2011.10.057