Acridine, 3-amino-6-chloro-

Base Information

• Chemical Name: Acridine, 3-amino-6-chloro-
• CAS No.: 40505-21-3
• Molecular Formula: C13H9ClN2
• Molecular Weight: 228.68
• NSC Number: 509736
• UNII: V83X956RR5
• DSSTox Substance ID: DTXSID50193517
• Nikkaji Number: J55.083C
• Wikidata: Q83066260
• ChEMBL ID: CHEMBL342982
• Mol file: 40505-21-3.mol

Synonyms:6-chloroacridin-3-amine;ACRIDINE, 3-AMINO-6-CHLORO-;3-Acridinamine, 6-chloro-;40505-21-3;6-Chloro-3-acridinamine;2-Amino-8-chloroacridine (European);NSC 509736;BRN 0166486;NSC-509736;4-22-00-04989 (Beilstein Handbook Reference);NSC509736;3-Amino-6-chloroacridine;Clc1ccc2cc3ccc(N)cc3nc2c1;CHEMBL342982;SCHEMBL11057520;DTXSID50193517;V83X956RR5

Chemical Property of Acridine, 3-amino-6-chloro-

Chemical Property:

• Vapor Pressure: 1.68E-08mmHg at 25°C
• Boiling Point: 456°C at 760 mmHg
• Flash Point: 229.6°C
• PSA: 38.91000
• Density: 1.384g/cm³
• LogP: 4.20480
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 228.0454260
• Heavy Atom Count: 16
• Complexity: 258

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC2=NC3=C(C=CC(=C3)Cl)C=C21)N

Technology Process of Acridine, 3-amino-6-chloro-

There total 6 articles about Acridine, 3-amino-6-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-amino-6-chloro-10H-acridin-9-one (99514-18-8) → 2-Amino-8-chloroacridin (40505-21-3)

Guidance literature:

With sodium amalgam; ethanol; sodium hydrogencarbonate; anschliessendes Behandeln mit Luft;

DOI:10.1039/jr9420000377

Reference yield:

2,4-dinitrobenzaldehyde (528-75-6) → 2-Amino-8-chloroacridin (40505-21-3)

Guidance literature:

Multi-step reaction with 4 steps

1: H₂SO₄; chlorobenzene

2: sodium nitrite; sulfuric acid

3: SnCl₂; aq.-ethanolic HCl

4: NaHCO₃; ethanol; sodium-amalgam / anschliessendes Behandeln mit Luft

With hydrogenchloride; sodium amalgam; ethanol; sulfuric acid; sodium hydrogencarbonate; chlorobenzene; tin(ll) chloride; sodium nitrite;

DOI:10.1039/jr9420000377

Reference yield:

3-chloro-6-nitro-10H-acridin-9-one (66909-59-9) → 2-Amino-8-chloroacridin (40505-21-3)

Guidance literature:

Multi-step reaction with 2 steps

1: SnCl₂; aq.-ethanolic HCl

2: NaHCO₃; ethanol; sodium-amalgam / anschliessendes Behandeln mit Luft

With hydrogenchloride; sodium amalgam; ethanol; sodium hydrogencarbonate; tin(ll) chloride;

DOI:10.1039/jr9420000377

upstream raw materials:

3-amino-6-chloro-10H-acridin-9-one

2,4-dinitrobenzaldehyde

3-chloro-6-nitro-10H-acridin-9-one

3-(4-chloro-phenyl)-6-nitro-benz[c]isoxazole