C₁₉H₁₆N₄O₈

Base Information

• Chemical Name: C₁₉H₁₆N₄O₈
• CAS No.: 1449676-90-7
• Molecular Formula: C₁₉H₁₆N₄O₈
• Molecular Weight: 428.358
• Mol file: 1449676-90-7.mol

Synonyms:C₁₉H₁₆N₄O₈

Chemical Property of C₁₉H₁₆N₄O₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₉H₁₆N₄O₈

There total 2 articles about C₁₉H₁₆N₄O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-nitro-4-(2-nitrovinyl)benzene (3156-41-0) + N-(4-nitrophenyl)-2-oxocyclobutanecarboxamide (1449676-72-5) → C19H16N4O8 (1449676-90-7) + C19H16N4O8

Guidance literature:

With C₃₂H₂₈F₆N₄O₂; In dichloromethane; at 22 ℃; for 0.5h; Overall yield = 62 %; Overall yield = 50.5 mg; enantioselective reaction;

DOI:10.1002/adsc.201200658

Reference yield:

1-nitro-4-(2-nitrovinyl)benzene (3156-41-0) + N-(4-nitrophenyl)-2-oxocyclobutanecarboxamide (1449676-72-5) → C19H16N4O8 (1449676-90-7)

Guidance literature:

With C₃₂H₂₈F₆N₄O₂; In dichloromethane; enantioselective reaction; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.201900159

Reference yield: 44.0%

C19H16N4O8 (1449676-90-7) → C19H16N4O8

Guidance literature:

With 3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine; In dichloromethane; at 28 ℃; for 15h; Inert atmosphere; Sealed tube;

DOI:10.1002/adsc.201900159

upstream raw materials:

1-nitro-4-(2-nitrovinyl)benzene

N-(4-nitrophenyl)-2-oxocyclobutanecarboxamide

Refernces

• 1、 Mailhol, Damien,Duque, Maria Del Mar Sanchez,Raimondi, Wilfried,Bonne, Damien,Constantieux, Thierry,Coquerel, Yoann,Rodriguez, Jean. "Enantioselective organocatalytic michael addition of cyclobutanones to nitroalkenes". . p. 3523 - 3532. Retrieved 2013/02/25.