(2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate

Base Information

Chemical Name:(2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate
CAS No.:388072-24-0
Molecular Formula:C₂HF₃O₂*C₁₈H₂₂F₂N₂O₂
Molecular Weight:450.406
Hs Code.:

Synonyms:(2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate

Suppliers and Price of (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate

Chemical Property:

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Technology Process of (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate

There total 1 articles about (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 388071-80-5
(1S,2R)-[1-(3,5-difluorobenzyl)-2-hydroxy-3-(3-methoxybenzylamino)propyl]-carbamic acid tert-butyl ester

: 76-05-1
trifluoroacetic acid

: 388072-24-0
(2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate

Guidance literature:: In dichloromethane; at 20 - 25 ℃; for 1h;

Reference yield:

: 388072-25-1
3-methyl-5-[(dipropylamino)carbonyl]benzoic acid

: 388072-24-0
(2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate

: N¹-{(2S,3R)-1-(3,5-difluorophenyl)-3-hydroxy-4-[(3-methoxybenzyl)amino]butan-2-yl}-5-methyl-N³,N³-dipropylisophthalamide

Guidance literature:: 3-methyl-5-[(dipropylamino)carbonyl]benzoic acid; (2R,3S)-3-amino-4-(3,5-difluorophenyl)-1-[(3-methoxybenzyl)amino]-2-butanol trifluoroacetate; With triethylamine; In DMF (N,N-dimethyl-formamide); at 0 - 25 ℃;

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In DMF (N,N-dimethyl-formamide); at 0 - 25 ℃; for 15h;