(1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene

Base Information

• Chemical Name: (1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene
• CAS No.: 1353742-23-0
• Molecular Formula: C₂₇H₂₈O₃
• Molecular Weight: 400.518
• Mol file: 1353742-23-0.mol

Synonyms:(1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene

Chemical Property of (1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

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Technology Process of (1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene

There total 27 articles about (1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

(1R,2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-cyclopentyl methanesulfonate (1353742-21-8) → (1R,2R,5R)-1,2-bis(benzyloxy)-5-((benzyloxy)methyl)cyclopent-3-ene (1353742-22-9) + (1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene (1353742-23-0)

Guidance literature:

With sodium hydride; In methanol; N,N-dimethyl-formamide; mineral oil; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ol203213f

Reference yield: 4.0%

(1R,2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-cyclopentyl methanesulfonate (1353742-21-8) → (1R,2R)-1,2-bis(benzyloxy)-5-methylenecyclopent-3-ene (1353742-24-1) + (1R,2R,5R)-1,2-bis(benzyloxy)-5-((benzyloxy)methyl)cyclopent-3-ene (1353742-22-9) + (1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene (1353742-23-0)

Guidance literature:

With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1021/ol203213f

Reference yield: 4.0%

(1R,2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-cyclopentyl methanesulfonate (1353742-21-8) → (1R,2R,5R)-1,2-bis(benzyloxy)-5-((benzyloxy)methyl)cyclopent-3-ene (1353742-22-9) + (1R,2R)-1,2-bis(benzyloxy)-3-((benzyloxy)methyl)cyclopent-3-ene (1353742-23-0) + (1R,2R)-1,2-bis(benzyloxy)-5-methylenecyclopent-3-ene

Guidance literature:

(1R,2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-cyclopentyl methanesulfonate; With potassium tert-butylate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h; Inert atmosphere;

With hydrogenchloride; In water; N,N-dimethyl-formamide; Inert atmosphere;

DOI:10.1002/chem.201202374

upstream raw materials:

(1R,2S)-2-((benzyloxy)methyl)cyclopent-3-en-1-yl methanesulfonate

(1R,2R,3R,5S)-2-((benzyloxy)methyl)-6-oxabicyclo[3.1.0]hexan-3-yl methanesulfonate

(1R,2R,3R,4R)-4-(benzyloxy)-2-((benzyloxy)methyl)-3-hydroxycyclopentyl methanesulfonate

(1R,2R,3R,4R)-3,4-bis(benzyloxy)-2-((benzyloxy)methyl)-cyclopentyl methanesulfonate