cis-2,3-Dimethylaziridine

Base Information

• Chemical Name: cis-2,3-Dimethylaziridine
• CAS No.: 930-19-8
• Molecular Formula: C₄H₉N
• Molecular Weight: 71.1222
• UNII: EJ4L2WU87T
• Nikkaji Number: J1.793.963G
• Mol file: 930-19-8.mol

Synonyms:cis-2,3-Dimethylaziridine;EJ4L2WU87T;2,3-Dimethylaziridine, cis-;930-19-8;Aziridine, 2,3-dimethyl-, cis-;Rel-(2R,3S)-2,3-dimethylaziridine;UNII-EJ4L2WU87T;NSC-152117;Aziridine, 2,3-dimethyl-, (2R,3S)-rel-;AKOS006351682

Chemical Property of cis-2,3-Dimethylaziridine

Chemical Property:

• Vapor Pressure: 216mmHg at 25°C
• Boiling Point: 57.6°C at 760 mmHg
• Density: 0.796g/cm³
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 71.073499291
• Heavy Atom Count: 5
• Complexity: 36.9

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(N1)C
• Isomeric SMILES: C[C@@H]1[C@@H](N1)C

Technology Process of cis-2,3-Dimethylaziridine

There total 6 articles about cis-2,3-Dimethylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

threo-2-Azido-3-iodobutane (4098-12-8) → cis-2,3-Dimethylaziridine (930-19-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 12h; Ambient temperature;

DOI:10.1021/jo00296a070

Reference yield:

→ cis-2,3-Dimethylaziridine (930-19-8)

Guidance literature:

With sulfuric acid; Das Reaktionsprodukt mit wss. Kalilauge behandeln, zuletzt unter Erwaermen_.;

DOI:10.1021/ja01124a023

Reference yield:

→ trans-2,3-Dimethylaziridin (930-19-8,930-20-1,2549-68-0,88876-97-5)

Guidance literature:

With sulfuric acid; at 250 ℃; (+-)-trans-2,3-dimethyl-aziridine; Das Reaktionsprodukt mit wss. Natronlauge erwaermen.;

upstream raw materials:

threo-2-Azido-3-iodobutane

Downstream raw materials:

N-((1RS,2RS)-2-chloro-1-methyl-propyl)-benzenesulfonamide

cis-2,3-dimethyl-N-tosylaziridine

1-Benzyl-cis-2,3-dimethylaziridine

α-<(cis-2,3-dimethyl-1-aziridinyl)methyl>-2-nitro-1H-imidazole-1-ethanol