N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide

Base Information

• Chemical Name: N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide
• CAS No.: 1259301-50-2
• Molecular Formula: C₅₂H₈₀N₂O₂₂S
• Molecular Weight: 1117.27
• Mol file: 1259301-50-2.mol

Synonyms:N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide

Chemical Property of N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide

There total 1 articles about N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

N-(6-hydroxyhexyl)-N-tetradecyl-2-nitrobenzenesulfonyl amide (1259301-43-3) + acetic anhydride (108-24-7) + 2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide (4753-07-5) → N-(6-acetyloxyhexyl)-N-tetradecyl-2-nitrobenzenesulfonyl amide (1259301-46-6) + N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide (1259301-50-2) + N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-α-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonyl amide (1259301-51-3)

Guidance literature:

N-(6-hydroxyhexyl)-N-tetradecyl-2-nitrobenzenesulfonyl amide; 2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide; With cadmium(II) carbonate; silica gel; In toluene; for 3.5h; Reflux;

acetic anhydride; With pyridine; at 20 - 23 ℃; for 4h;

DOI:10.1134/S1068162010050146

Reference yield: 68.0%

N-[6-(2,2',3,3',4',6,6'-hepta-O-acetyl-β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonylamide (1259301-50-2) → N-[6-(β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonyl amide (1259301-52-4)

Guidance literature:

With sodium methylate; In methanol; at 23 ℃; for 0.5h;

DOI:10.1134/S1068162010050146

upstream raw materials:

N-(6-hydroxyhexyl)-N-tetradecyl-2-nitrobenzenesulfonyl amide

acetic anhydride

2,3,6,2',3',4',6'-hepta-O-acetyl-lactosyl bromide

Downstream raw materials:

N-[6-(β-lactosyloxy)hexyl]-N-tetradecyl-2-nitrobenzenesulfonyl amide