N₁-(2-aminophenyl)-N₈-[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl]-N₈-(phenylmethyl)-octanediamide

Base Information

• Chemical Name: N₁-(2-aminophenyl)-N₈-[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl]-N₈-(phenylmethyl)-octanediamide
• CAS No.: 1147752-42-8
• Molecular Formula: C₄₄H₄₈N₄O₃
• Molecular Weight: 680.89

Synonyms:N₁-(2-aminophenyl)-N₈-[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl]-N₈-(phenylmethyl)-octanediamide

Chemical Property of N₁-(2-aminophenyl)-N₈-[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl]-N₈-(phenylmethyl)-octanediamide

Chemical Property:

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Technology Process of N₁-(2-aminophenyl)-N₈-[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl]-N₈-(phenylmethyl)-octanediamide

There total 1 articles about N₁-(2-aminophenyl)-N₈-[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl]-N₈-(phenylmethyl)-octanediamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

8-[[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl](phenylmethyl)amino]-8-oxo-octanoic acid (1147752-30-4) + 1,2-diamino-benzene (95-54-5) → N1-(2-aminophenyl)-N8-[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl]-N8-(phenylmethyl)-octanediamide (1147752-42-8)

Guidance literature:

With dicyclohexyl-carbodiimide; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jm801529c

upstream raw materials:

8-[[1-([1,1'-biphenyl]-4-ylmethyl)-2-oxo-2-[(2-phenylethyl)amino]ethyl](phenylmethyl)amino]-8-oxo-octanoic acid

1,2-diamino-benzene

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