[4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid

Base Information

Chemical Name:[4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid
CAS No.:948317-79-1
Molecular Formula:C₁₂H₁₅NO₉P₂
Molecular Weight:379.2
Hs Code.:

Synonyms:[4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of [4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid

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Technology Process of [4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid

There total 1 articles about [4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 85-44-9
phthalic anhydride

: 948317-79-1
[4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)-1-hydroxy-1-phosphonobutyl]phosphonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / 6 h / 170 °C

2: 100 percent / oxalyl chloride / CH₂Cl₂ / 6 h / Heating

3: 90 percent / tris(trimethylsilyl) phosphite / 4 h / 20 °C

With oxalyl dichloride; tris(trimethylsilyl) phosphite; In dichloromethane;
DOI:10.1002/ejoc.200601067