ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside

Base Information

• Chemical Name: ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside
• CAS No.: 226985-51-9
• Molecular Formula: C₂₁H₃₃BrO₄Si
• Molecular Weight: 457.48
• Mol file: 226985-51-9.mol

Synonyms:ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside

Chemical Property of ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside

There total 1 articles about ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

ethyl 6-O-tert-butyldimethylsilyl-4-hydroxyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside (58888-62-3) + 1-Bromo-2-bromomethyl-benzene (3433-80-5) → ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside (226985-51-9)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 60 ℃; for 24h;

DOI:10.1055/s-1999-2717

Reference yield: 50.0%

ethyl 4-O-(2-bromobenzyl)-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside (226985-51-9) → Ethyl 4-O-benzyl-6-O-(tert-butyldimethylsilyl)-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside

Guidance literature:

With water; tetra(n-butyl)ammonium hydrogensulfate; triethylamine; palladium diacetate; triphenylphosphine; In acetonitrile;

DOI:10.1055/s-1999-2717

upstream raw materials:

ethyl 6-O-tert-butyldimethylsilyl-4-hydroxyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside

1-Bromo-2-bromomethyl-benzene