3-(R)-amino-2-(S)-[(4’-ethylbiphenyl-4-carbonyl)amino]butylhydroxamic acid hydrochloride

Base Information

Chemical Name:3-(R)-amino-2-(S)-[(4’-ethylbiphenyl-4-carbonyl)amino]butylhydroxamic acid hydrochloride
CAS No.:728879-21-8
Molecular Formula:C₁₉H₂₃N₃O₃*ClH
Molecular Weight:377.871
Hs Code.:

Synonyms:3-(R)-amino-2-(S)-[(4’-ethylbiphenyl-4-carbonyl)amino]butylhydroxamic acid hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(R)-amino-2-(S)-[(4’-ethylbiphenyl-4-carbonyl)amino]butylhydroxamic acid hydrochloride

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Technology Process of 3-(R)-amino-2-(S)-[(4’-ethylbiphenyl-4-carbonyl)amino]butylhydroxamic acid hydrochloride

There total 1 articles about 3-(R)-amino-2-(S)-[(4’-ethylbiphenyl-4-carbonyl)amino]butylhydroxamic acid hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5731-13-5
4-(4-ethylphenyl)benzoic acid

: 728879-21-8
3-(R)-amino-2-(S)-[(4’-ethylbiphenyl-4-carbonyl)amino]butylhydroxamic acid hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 24 h / Inert atmosphere

2: hydrogen; palladium 10% on activated carbon / methanol / 3 h / 120 °C / 760.05 Torr / Sonication; Inert atmosphere

3: sodium methylate; hydroxylamine hydrochloride / methanol; dichloromethane / 20 °C / Inert atmosphere

With palladium 10% on activated carbon; hydroxylamine hydrochloride; hydrogen; sodium methylate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In methanol; dichloromethane;