(R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline

Base Information

Chemical Name:(R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline
CAS No.:1060720-27-5
Molecular Formula:C₂₂H₂₄FN₃O
Molecular Weight:365.45
Hs Code.:

Synonyms:(R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline

Suppliers and Price of (R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline

Chemical Property:

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Technology Process of (R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline

There total 2 articles about (R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

: 1060720-59-3
(R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-nitroisoquinoline

: 1060720-27-5
(R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline

Guidance literature:: With tetrabutyl ammonium fluoride; In N,N-dimethyl-formamide; at 140 - 155 ℃; for 2.5h;

Reference yield:

: 502482-35-1
(R)-1-benzyl-3-(methoxymethyl)piperazine

: 1060720-27-5
(R)-1-[4'-benzyl-2'-(methoxymethyl)piperazin-1'-yl]-5-fluoroisoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 4 h / 130 - 150 °C

2: tetrabutyl ammonium fluoride / N,N-dimethyl-formamide / 2.5 h / 140 - 155 °C

With tetrabutyl ammonium fluoride; In N,N-dimethyl-formamide;