Tyrphostin B44, (-) enantiomer

Base Information

Chemical Name:Tyrphostin B44, (-) enantiomer
CAS No.:133550-32-0
Molecular Formula:C₁₈H₁₆N₂O₃
Molecular Weight:308.337
Hs Code.:
DSSTox Substance ID:DTXSID90416171
Nikkaji Number:J412.916D,J1.956.941A
ChEMBL ID:CHEMBL258767
Mol file:133550-32-0.mol

Synonyms:alpha-cyano-N-(alpha-phenethyl)-3,4-dihydroxycinnamide;N-(alpha-methylbenzyl)-3,4-dihydroxybenzylidine cyanoacetamide;tyrphostin B44;tyrphostin B50(+)

Suppliers and Price of Tyrphostin B44, (-) enantiomer

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tyrphostin B44,
10mg
$ 366.00

Usbiological
Tyrphostin B44,
10mg
$ 366.00

TRC
TyrphostinB44,(-)enantiomer
50mg
$ 255.00

TRC
TyrphostinB44,(-)enantiomer
5mg
$ 40.00

TRC
TyrphostinB44,(-)enantiomer
100mg
$ 475.00

American Custom Chemicals Corporation
(-)-TYRPHOSTIN B44 95.00%
25MG
$ 727.65

Total 11 raw suppliers

Chemical Property of Tyrphostin B44, (-) enantiomer

Chemical Property:

Vapor Pressure:3.9E-15mmHg at 25°C
Boiling Point:603°C at 760 mmHg
Flash Point:318.5°C
PSA：93.35000
Density:1.299g/cm³
LogP:3.27308
Storage Temp.:−20°C
Solubility.:DMSO or ethanol: soluble
XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:308.11609238
Heavy Atom Count:23
Complexity:488

Purity/Quality:

97% ^*data from raw suppliers

Tyrphostin B44, ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=CC=C1)NC(=O)C(=CC2=CC(=C(C=C2)O)O)C#N
Isomeric SMILES:C[C@H](C1=CC=CC=C1)NC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N
Uses Tyrphostin B44, (-) enantiomer is a potent inhibitor of (EGFR) kinase.

Technology Process of Tyrphostin B44, (-) enantiomer

There total 2 articles about Tyrphostin B44, (-) enantiomer which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%