Chemical Property of 1-Phthalazinamine, N-(3-chlorophenyl)-4-phenyl-
Chemical Property:
- Vapor Pressure:1.02E-11mmHg at 25°C
- Boiling Point:539.7°C at 760 mmHg
- Flash Point:280.2°C
- PSA：37.81000
- Density:1.31g/cm3
- LogP:5.76680
- Storage Temp.:Store at RT
- XLogP3:5.3
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:3
- Exact Mass:331.0876252
- Heavy Atom Count:24
- Complexity:398
- Purity/Quality:
-
97% *data from raw suppliers
MY-5445 *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=CC=C(C=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC(=CC=C4)Cl
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Description
MY-5445 is a selective inhibitor of the cyclic GMP (cGMP) phosphodiesterase, PDE5, with a Ki value of 1.3 μM. It inhibits calcium- and cAMP-selective PDEs with Ki values of >1,000 and 915 μM, respectively. MY-5445 has been shown to relax intact strips of rat aorta with an EC50 value of 4 μM.
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Uses
MY-5445 is a selective cGMP phosphodiesterase inhibitor. Potent PDE5 inhibitor.
