1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonyl chloride

Base Information

Chemical Name:1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonyl chloride
CAS No.:107144-42-3
Molecular Formula:C₁₀H₉BrClNO₃S
Molecular Weight:338.609
Hs Code.:
European Community (EC) Number:888-846-4
Mol file:107144-42-3.mol

Synonyms:107144-42-3;1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonyl chloride;5-bromo-1-acetyl-2,3-dihydro-1H-indole-6-sulfonyl chloride;1-acetyl-5-bromo-2,3-dihydroindole-6-sulfonyl chloride;1-acetyl-5-bromoindoline-6-sulfonyl chloride;LCZC3510;SCHEMBL1179278;IHNBWFJSLLIAPD-UHFFFAOYSA-N;5-bromo-6-chlorosulfonyl-N-acetylindoline;EN300-50854;G43484;J-001716;1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonylchloride

Suppliers and Price of 1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

AK Scientific
1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonylchloride
250mg
$ 301.00

Total 1 raw suppliers

Chemical Property of 1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonyl chloride

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:336.91750
Heavy Atom Count:17
Complexity:422

Purity/Quality:: 1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonylchloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)N1CCC2=CC(=C(C=C21)S(=O)(=O)Cl)Br

Technology Process of 1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonyl chloride

There total 3 articles about 1-Acetyl-5-bromo-2,3-dihydro-1H-indole-6-sulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 22190-38-1
5-bromo-N-acetylindoline

: 107144-42-3
1‐acetyl 5‐bromoindoline‐6‐sulfonyl chloride

Guidance literature:: With chlorosulfonic acid; at 70 ℃; Inert atmosphere; Cooling with ice;

Reference yield:

: 16078-30-1
1-Acetyl-2,3-dihydro-1H-indole

: 107144-42-3
1‐acetyl 5‐bromoindoline‐6‐sulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / acetic acid / 0.17 h / 20 °C / Inert atmosphere

2: chlorosulfonic acid / 12 h / 80 °C / Inert atmosphere; Neat (no solvent)

With chlorosulfonic acid; bromine; In acetic acid;
DOI:10.1002/adsc.201000465

Reference yield:

: 496-15-1
1-indoline

: 107144-42-3
1‐acetyl 5‐bromoindoline‐6‐sulfonyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1: dichloromethane / 0.5 h / 20 °C / Inert atmosphere

2: bromine / acetic acid / 0.17 h / 20 °C / Inert atmosphere

3: chlorosulfonic acid / 12 h / 80 °C / Inert atmosphere; Neat (no solvent)

With chlorosulfonic acid; bromine; In dichloromethane; acetic acid;
DOI:10.1002/adsc.201000465