Technology Process of C33H54O3Si2
There total 9 articles about C33H54O3Si2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(2S,3S,8S)-3-(tert-butyldimethylsilyloxy)-9-(tert-butyldiphenylsilyloxy)-2,8-dimethylnonan-1-ol;
With
oxalyl dichloride; dimethyl sulfoxide;
In
dichloromethane;
at -78 ℃;
for 2h;
With
triethylamine;
In
dichloromethane;
DOI:10.1016/j.tet.2012.11.075
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: titanium tetrachloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.42 h / 0 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: 2,6-dimethylpyridine / dichloromethane / 0.17 h / 0 °C
3.1: lithium borohydride / methanol / 0.5 h / 0 °C / Inert atmosphere
4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 2 h / -78 °C
With
2,6-dimethylpyridine; lithium borohydride; oxalyl dichloride; titanium tetrachloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
methanol; dichloromethane;
1.2: |Evans Aldol Reaction / 4.1: |Swern Oxidation / 4.2: |Swern Oxidation;
DOI:10.1016/j.tet.2012.11.075
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: 1H-imidazole / dichloromethane / 0.25 h / 0 °C
1.2: 2 h / 20 °C
2.1: ozone / dichloromethane / 0.25 h / -78 °C
2.2: 0.17 h / Reflux
3.1: sodium tetrahydroborate; nickel(II) chloride hexahydrate; hydrogen / methanol / 4 h / 0 - 20 °C
4.1: diisobutylaluminium hydride / dichloromethane; toluene / 2 h / -78 °C
5.1: titanium tetrachloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.42 h / 0 °C / Inert atmosphere
5.2: 2 h / -78 °C / Inert atmosphere
6.1: 2,6-dimethylpyridine / dichloromethane / 0.17 h / 0 °C
7.1: lithium borohydride / methanol / 0.5 h / 0 °C / Inert atmosphere
8.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 2 h / -78 °C
With
1H-imidazole; 2,6-dimethylpyridine; sodium tetrahydroborate; lithium borohydride; oxalyl dichloride; nickel(II) chloride hexahydrate; hydrogen; titanium tetrachloride; diisobutylaluminium hydride; ozone; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine;
In
methanol; dichloromethane; toluene;
2.2: |Wittig Olefination / 5.2: |Evans Aldol Reaction / 8.1: |Swern Oxidation / 8.2: |Swern Oxidation;
DOI:10.1016/j.tet.2012.11.075
