4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

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Chemical Name:4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one
CAS No.:435343-16-1
Molecular Formula:C₂₃H₁₉ClN₄O₂S
Molecular Weight:450.948
Hs Code.:

Synonyms:4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

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Chemical Property of 4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

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Technology Process of 4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

There total 2 articles about 4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 361186-08-5
4-((2-chloroquinolin-3-yl)methyleneamino)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

: 68-11-1
mercaptoacetic acid

: 435343-16-1
4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

Guidance literature:: In neat (no solvent); at 170 ℃; Microwave irradiation; Green chemistry;
DOI:10.1080/10426507.2013.769977

Reference yield:

: 73568-25-9
2-chloro-3-quinoline carboxaldehyde

: 83-07-8
4-amino-2,3-dimethyl-1-phenylpyrazolin-5-one

: 435343-16-1
4-(2-(2-chloroquinolin-3-yl)-4-oxothiazolidin-3-yl)-1,2-dihydro-2,3-dimethyl-1-phenylpyrazol-5-one

Guidance literature:: Multi-step reaction with 2 steps

1: neat (no solvent) / 140 °C / Microwave irradiation; Green chemistry

2: / neat (no solvent) / 170 °C / Microwave irradiation; Green chemistry

In neat (no solvent);
DOI:10.1080/10426507.2013.769977