Thioproperazine

Base Information

Chemical Name:Thioproperazine
CAS No.:316-81-4
Molecular Formula:C22H30 N4 O2 S2
Molecular Weight:446.638
Hs Code.:2935009090
European Community (EC) Number:206-262-4
UNII:YJ050AQ56X
DSSTox Substance ID:DTXSID1023655
Nikkaji Number:J5.665K
Wikipedia:Thioproperazine
Wikidata:Q2622839
NCI Thesaurus Code:C73292
Metabolomics Workbench ID:43606
ChEMBL ID:CHEMBL609109
Mol file:316-81-4.mol

Synonyms:Majeptil;thioproperazine;thioproperazine mesylate

Suppliers and Price of Thioproperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Thioproperazine 97%
1g
$ 1664.00

Crysdot
Thioproperazine 97%
250mg
$ 665.00

Crysdot
Thioproperazine 97%
100mg
$ 416.00

Total 33 raw suppliers

Chemical Property of Thioproperazine

Chemical Property:

Vapor Pressure:6.32E-15mmHg at 25°C
Melting Point:140ºC
Refractive Index:1.615
Boiling Point:612.2°Cat760mmHg
PKA:7.65±0.10(Predicted)
Flash Point:324°C
PSA：80.78000
Density:1.237g/cm³
LogP:4.19870
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:6
Exact Mass:446.18101856
Heavy Atom Count:30
Complexity:661

Purity/Quality:

97% ^*data from raw suppliers

Thioproperazine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)CCCN2C3=CC=CC=C3SC4=C2C=C(C=C4)S(=O)(=O)N(C)C
Therapeutic Function Neuroleptic, Antiemetic

Technology Process of Thioproperazine

There total 6 articles about Thioproperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1217018-61-5
N-(3-chloropropyl)-4-methylpiperazine hydrochloride

: 1090-78-4
10H-phenothiazine-2-sulfonic acid dimethylamide

: 316-81-4
thioproperazine

Guidance literature:: Multistep reaction; (i) NaOH, toluene, (ii) /BRN= 4792564/;
DOI:10.1007/BF00771334

Reference yield:

: 316-81-4
thioproperazine

Guidance literature:: Phenothiazin VII, Piperazin IX;

Reference yield:

: 5510-56-5
(2-Amino-phenyl)-(4-dimethylsulfamino-2-nitro-phenyl)-sulfid

: 316-81-4
thioproperazine

Guidance literature:: Multi-step reaction with 3 steps

1: H₂O / Heating

2: aq. NaOH / ethanol; acetone / Heating

3: (i) NaOH, toluene, (ii) /BRN= 4792564/

With sodium hydroxide; In ethanol; water; acetone;
DOI:10.1007/BF00771334