diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate

Base Information

Chemical Name:diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate
CAS No.:1375111-08-2
Molecular Formula:C₂₂H₂₃N₃O₅
Molecular Weight:409.442
Hs Code.:

Synonyms:diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate

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Technology Process of diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate

There total 3 articles about diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 442869-54-7
2-(3-methoxyphenyl)imidazo[1,2-a]pyridin-8-amine

: 87-13-8
diethyl 2-ethoxymethylenemalonate

: 1375111-08-2
diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate

Guidance literature:: In toluene; for 27h; Reflux;
DOI:10.1016/j.ejmech.2012.03.011

Reference yield:

: 452-58-4
2,3-Diaminopyridine

: 1375111-08-2
diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 24 h / Reflux

2: toluene / 27 h / Reflux

In ethanol; toluene;
DOI:10.1016/j.ejmech.2012.03.011

Reference yield:

: 5000-65-7
2-bromo-3'-methoxyacetophenone

: 1375111-08-2
diethyl N-(2-(3'-methoxyphenyl)imidazo[1,2-a]pyridin-8-yl)aminomethylenemalonate

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 24 h / Reflux

2: toluene / 27 h / Reflux

In ethanol; toluene;
DOI:10.1016/j.ejmech.2012.03.011