2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide

Base Information

Chemical Name:2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide
CAS No.:107300-97-0
Molecular Formula:C₂₂H₃₁N₃O₄
Molecular Weight:401.506
Hs Code.:

Synonyms:2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide

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Chemical Property of 2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide

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Technology Process of 2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide

There total 1 articles about 2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 3289-28-9
ethyl cyclohexanecarboxylate

: 107301-08-6
2-<<-2-(3,4-diethoxyphenyl)ethyl>carbamoyl>acetamide oxime

: 107300-97-0
2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide

Guidance literature:: With sodium ethanolate; In ethanol; for 4h; Heating;

Reference yield: 79.0%

: 107300-97-0
2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide

: 107301-23-5
1-(5-Cyclohexyl-[1,2,4]oxadiazol-3-ylmethyl)-6,7-diethoxy-3,4-dihydro-isoquinoline

Guidance literature:: With trichlorophosphate; In chloroform; for 3h; Heating;

Reference yield:

: 107300-97-0
2-(5-Cyclohexyl-[1,2,4]oxadiazol-3-yl)-N-[2-(3,4-diethoxy-phenyl)-ethyl]-acetamide

: 107301-47-3
4-Cyclohexyl-9,10-diethoxy-6,7-dihydro-pyrimido[6,1-a]isoquinolin-2-ylideneamine; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 79 percent / POCl₃ / CHCl₃ / 3 h / Heating

2: 65 percent / H₂, 10percent HCl / 8percent Pd/C / ethanol / 60 °C

With hydrogenchloride; hydrogen; trichlorophosphate; palladium on activated charcoal; In ethanol; chloroform;