methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride

Base Information

• Chemical Name: methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride
• CAS No.: 56290-92-7
• Molecular Formula: C₂₁H₂₅NO₆*ClH
• Molecular Weight: 423.894
• Mol file: 56290-92-7.mol

Synonyms:methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride

Chemical Property of methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride

There total 1 articles about methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

5-[2-(3-Benzo[1,3]dioxol-5-yl-1-methyl-propylamino)-acetyl]-2-hydroxy-benzoic acid methyl ester; hydrochloride (56290-91-6) → methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride (56290-92-7)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; for 11.5h;

DOI:10.1021/jm00135a017

Reference yield: 81.0%

methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride (56290-92-7) → Medroxalol hydrochloride (70161-10-3)

Guidance literature:

With ammonium hydroxide; for 192h; Ambient temperature;

DOI:10.1021/jm00348a013

Reference yield:

methyl 5-(2-{[3-(1,3-benzodioxol-5-yl)-1-methylpropyl]amino}-1-hydroxyethyl)-2-hydroxybenzoate hydrochloride (56290-92-7) → 5-<2-<<3-(1,3-benzodioxol-5-yl)-1-methylpropyl>amino>-1-hydroxyethyl>-2-hydroxybenzoic acid

Guidance literature:

With sodium hydroxide; at 100 ℃; for 1.3h;

DOI:10.1021/jm00135a017

upstream raw materials:

5-[2-(3-Benzo[1,3]dioxol-5-yl-1-methyl-propylamino)-acetyl]-2-hydroxy-benzoic acid methyl ester; hydrochloride

Downstream raw materials:

Medroxalol hydrochloride