N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

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Chemical Name:N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide
CAS No.:1422748-31-9
Molecular Formula:C₁₁₅H₁₉₇N₂O₁₈P
Molecular Weight:1926.81
Hs Code.:

N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

Synonyms:N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

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Chemical Property of N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

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Technology Process of N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

There total 1 articles about N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1428739-46-1
N-{2-(tert-butyldiphenylsilyloxy)ethyl}-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

: 1422748-31-9
N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

Guidance literature:: With tetrabutyl ammonium fluoride; acetic acid; In tetrahydrofuran; dichloromethane; at 20 ℃; for 18h;
DOI:10.1016/j.bmc.2013.02.024

Reference yield: 83.0%

: 1422748-31-9
N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

: 1428739-48-3
N-{carboxymethyl}-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; [bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1016/j.bmc.2013.02.024

Reference yield: 71.0%

: 1422748-31-9
N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

: 108549-23-1
Dibenzyl N,N-diisopropylphosphoramidite

: 1428739-47-2
N-{2-(di-O-benzylphosphono)ethyl}-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide

Guidance literature:: N-(2-hydroxyethyl)-N-{2-[6-O-benzyl-2-deoxy-4-O-(di-O-benzylphosphono)-3-O-((R)-3-tetradecanoyloxytetradecanoyl)-2-((R)-3-tetradecanoyloxytetradecanamido)-β-D-glucopyranosyloxy]ethyl}-(R)-3-tetradecanoyloxytetradecanamide; Dibenzyl N,N-diisopropylphosphoramidite; With 5-Phenyl-1H-tetrazole; In dichloromethane; at 20 ℃; for 0.5h;

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1016/j.bmc.2013.02.024