3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril

Base Information

• Chemical Name: 3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril
• CAS No.: 60550-50-7
• Molecular Formula: C₁₆H₂₃NOSi
• Molecular Weight: 273.45
• Mol file: 60550-50-7.mol

Synonyms:3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril

Chemical Property of 3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of 3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril

There total 1 articles about 3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-<(trimethylsilyl)oxy>-3-methyl-3-butenenitrile (60550-34-7) + 1-phenyl-2-bromoethane (103-63-9) → 3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril (60550-50-7)

Guidance literature:

Multistep reaction; (i) LDA, (ii) /BRN= 507487/;

DOI:10.1055/s-1976-24068

Reference yield: 93.0%

3-Methyl-2-(2-phenylethyl)-2-trimethylsiloxy-3-butennitril (60550-50-7) → 2-methyl-5-phenylpent-1-en-3-one (60550-54-1)

Guidance literature:

With triethylamine hydrofluoride; In tetrahydrofuran; Ambient temperature;

upstream raw materials:

2-<(trimethylsilyl)oxy>-3-methyl-3-butenenitrile

1-phenyl-2-bromoethane

Downstream raw materials:

2-methyl-5-phenylpent-1-en-3-one